Table 1.
Multivariate Survival Analysis of the Clinical Factors Associated With the Survival of NPC Patients Through the Cox Regression Model
| Variables | TSS | NDMS | NLRS | |||
|---|---|---|---|---|---|---|
| HR (95% CI) | p * | HR (95% CI) | p * | HR (95% CI) | p * | |
| Histological type | ||||||
| Differentiated versus undifferentiated | 1.669 (1.196–2.328) | 0.003 | 1.653 (1.183–2.311) | 0.003 | 1.514 (1.081–2.122) | 0.016 |
| T stage | ||||||
| T1–T2 versus T3–T4 | 3.230 (2.319–4.501) | <0.001 | 2.890 (1.988–4.201) | <0.001 | 2.913 (2.041–4.160) | <0.001 |
| N stage | ||||||
| N0–N1 versus N2–N3 | 2.410 (1.456–3.987) | 0.001 | 2.400 (1.447–3.980) | 0.001 | 2.422 (1.461–4.014) | 0.001 |
| CUL3 expression | ||||||
| Low versus high | 2.008 (1.304–3.096) | 0.002 | 1.901 (1.211–2.985) | 0.005 | 2.066 (1.337–3.195) | 0.001 |
| Ki-67 expression | ||||||
| Low versus high | 3.215 (2.066–5.000) | <0.001 | 3.247 (2.079–5.076) | <0.001 | 3.012 (1.923–4.717) | <0.001 |
TSS, tumor-specific survival; NDMS, no distant metastasis-specific survival; NLRS, no local recurrence-specific survival; HR, hazard ratio; CI, confidence interval.
*
Multivariate Cox proportional hazards model.