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. 2018 Mar 5;26(2):201–208. doi: 10.3727/096504017X14920318811749

Figure 2.

Figure 2

CCAT1 knockdown suppressed the proliferation and accelerated the apoptosis of melanoma cell lines (B16 and A375). (A) CCAT1 knockdown in melanoma cells transfected with si-CCAT1. (B, C) Cell viability was measured at indicated time points using the cell counting kit 8 (CCK-8) assay. (D) Clone number of colony formation assay. (E–G) CCAT1 induced cell cycle arrest at the G0/G1 phase. (H, I) Apoptosis of B16 and A375 cells detected by flow cytometry. Data are presented as the mean ± SD. *p < 0.05, **p < 0.01 compared to the si-NC group.