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miR-16 downregulated COX-2 expression via deactivation of NF-κB signaling pathway. (A) The mRNA levels of miR-16 in miR-16 mimic or NC-transfected cells were detected by qRT-PCR. (B) The expressions of the main factors in NF-κB signaling pathway were measured by Western blot analysis. COX-2, cyclooxygenase-2. ***p < 0.001.
