Table 1.
Clinicopathologic Variables | n | TROAP mRNA Expression | p Value | |
---|---|---|---|---|
Low | High | |||
Gender | 0.9748 | |||
Male | 45 | 26 | 19 | |
Female | 7 | 4 | 3 | |
Age (years) | 0.9125 | |||
≤60 | 47 | 27 | 20 | |
>60 | 5 | 3 | 2 | |
AFP (ng/ml) | 0.7459 | |||
<200 | 13 | 8 | 5 | |
≥200 | 39 | 22 | 17 | |
Cirrhosis | 0.6704 | |||
Absence | 4 | 2 | 2 | |
Presence | 48 | 28 | 20 | |
Child–Pugh Score | 0.3405 | |||
A | 34 | 18 | 16 | |
B | 18 | 12 | 6 | |
Tumor size (cm) | 0.0121* | |||
<3 | 35 | 16 | 19 | |
≥3 | 17 | 14 | 3 | |
Capsular formation | 0.3790 | |||
Presence | 3 | 1 | 2 | |
Absence | 49 | 29 | 20 | |
Tumor nodule number | 0.0035† | |||
Solitary | 39 | 18 | 21 | |
Multiple (≥2) | 13 | 12 | 1 | |
TNM stage | 0.3309 | |||
I–II | 39 | 21 | 18 | |
III | 13 | 9 | 4 | |
BCLC stage | 0.0412* | |||
0–A | 32 | 22 | 10 | |
B–C | 20 | 8 | 12 | |
Edmondson–Steiner | 0.6289 | |||
I–II | 17 | 9 | 8 | |
III–IV | 35 | 21 | 14 | |
Vein invasion | 0.0186* | |||
Presence | 19 | 15 | 4 | |
Absence | 33 | 15 | 18 |
AFP, α-fetoprotein; BCLC, barcelona clinic liver cancer; HCC, hepatocellular cancer; TNM, tumor–node–metastasis classification; TROAP, trophinin-associated protein.
*p < 0.05; †p < 0.01.