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. 2018 Jun 11;26(5):691–701. doi: 10.3727/096504017X15101398724809

Table 1.

Association of TROAP mRNA Expression With Clinicopathological Parameters in 52 HCC Specimens

Clinicopathologic Variables n TROAP mRNA Expression p Value
Low High
Gender 0.9748
 Male 45 26 19
 Female 7 4 3
Age (years) 0.9125
 ≤60 47 27 20
 >60 5 3 2
AFP (ng/ml) 0.7459
 <200 13 8 5
 ≥200 39 22 17
Cirrhosis 0.6704
 Absence 4 2 2
 Presence 48 28 20
Child–Pugh Score 0.3405
 A 34 18 16
 B 18 12 6
Tumor size (cm) 0.0121*
 <3 35 16 19
 ≥3 17 14 3
Capsular formation 0.3790
 Presence 3 1 2
 Absence 49 29 20
Tumor nodule number 0.0035†
 Solitary 39 18 21
 Multiple (≥2) 13 12 1
TNM stage 0.3309
 I–II 39 21 18
 III 13 9 4
BCLC stage 0.0412*
 0–A 32 22 10
 B–C 20 8 12
Edmondson–Steiner 0.6289
 I–II 17 9 8
 III–IV 35 21 14
Vein invasion 0.0186*
 Presence 19 15 4
 Absence 33 15 18

AFP, α-fetoprotein; BCLC, barcelona clinic liver cancer; HCC, hepatocellular cancer; TNM, tumor–node–metastasis classification; TROAP, trophinin-associated protein.

*p < 0.05; †p < 0.01.