Skip to main content
. 2018 Oct 17;26(9):1401–1409. doi: 10.3727/096504018X15188747585738

Figure 5.

Figure 5

Restoration of Notch1 expression reverses the suppressive effects of miR-744 mimics in CRC cells. miR-744 mimic or miR-NC was introduced into SW480 and HCT116 cells in combination with pcDNA3.1 or pcDNA3.1-Notch1. (A) Western blot analysis was conducted at 72 h posttransfection to determine Notch1 protein level. *p < 0.05 versus miR-NC. #p < 0.05 versus miR-744 mimic < pcDNA3.1-Notch1. (B) CCK-8 and (C) Matrigel invasion assays were used to detect the proliferation and invasion of the above-mentioned treated cells. *p < 0.05 versus miR-NC. #p < 0.05 versus miR-744 mimic < pcDNA3.1-Notch1.