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. 2018 May 7;26(4):655–664. doi: 10.3727/096504017X15119525209765

Figure 3.

Figure 3

MG132 increased cisplatin-induced apoptosis and proliferation inhibition in OS cells. MG-63 and HOS cells were treated with DMSO/5 μg/ml cisplatin/10 μM MG132/combined (5 μg/ml cisplatin + 10 μM MG132) for 24 h. (A–D) Morphological appearances of the cells were observed under an inverted phase-contrast microscope. (E, F) The CKK-8 assay was performed to determine the effect of MG132/cisplatin/combination on cell proliferation. *p < 0.05 versus control (DMSO) denotes a significant difference, #p < 0.05 versus MG132 or cisplatin denotes a significant difference.