Table 1.
Demographic Data of the Patients Treated With Tyrosine Kinase Inhibitors
Variables | Gefitinib (n = 83) | Erlotinib (n = 36) | Afatinib (n = 28) | p Value |
---|---|---|---|---|
Median age [year (range)] | 75 (50–95) | 72 (52–87) | 68 (37–82) | 0.014 |
Sex | 0.849 | |||
Female | 54 | 22 | 19 | |
Male | 29 | 14 | 9 | |
Smoking status | 0.153 | |||
Never | 58 | 18 | 22 | |
Former | 14 | 13 | 5 | |
Current | 9 | 2 | 1 | |
Unknown | 2 | 3 | 0 | |
Histological subtype | 0.120 | |||
Adenocarcinoma | 78 | 33 | 23 | |
Squamous cell carcinoma | 1 | 0 | 3 | |
Other | 4 | 3 | 2 | |
Clinical stage | 0.742 | |||
3A | 20 | 10 | 8 | |
3B | 5 | 3 | 3 | |
4 | 58 | 23 | 16 | |
Recurrent | 0 | 0 | 1 |