Figure 4.
Knockdown of lncRNA CRNDE promotes cell cycle arrest at the G1 phase and causes cell apoptosis. (A, C) Flow cytometric analysis of cell cycle distribution (A) and apoptosis (C) was utilized to determine the effect of CRNDE on the cell cycle and apoptosis rate. (B, D) Western blot was performed to assess the function of CRNDE on p21 and CDK2 (B), and cleaved caspase 3 and cleaved caspase 9 (D). Data are represented as the mean ± SD from three independent experiments. The p value represents the comparison between groups (**p < 0.01).