Skip to main content
. 2018 Mar 5;26(2):191–200. doi: 10.3727/096504017X14965111926391

Figure 3.

Figure 3

Effect of CA IX inhibition on cell biological effects under normoxic and hypoxic conditions. (A) Cytotoxicity when CA IX was blocked with increasing concentrations of U104 (SRB assay, 72 h, 20% O2; n = 8–9). (B) Relative caspase 3 activity in the presence of 50 μM U104 compared to vehicle under hypoxic conditions (0.2% O2; n = 4–8). Relative changes in (C) caspase 3 activity, (D) LDH release, and (E) cellular protein after 3 h of incubation with 50 μM U104 under normoxic conditions (20% O2; vehicle = 100%, n = 4–8). *p < 0.05.