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. 2018 Sep 14;26(8):1275–1283. doi: 10.3727/096504018X15185735627746

Figure 4.

Figure 4

Restored MACC1 expression counteracts the suppressive effects of miR-598 overexpression on U87 and U251 cells. pCMV-MACC1 or pCMV was introduced into U87 and U251 cells in the presence of ectopic miR-598 expression. (A) Western blot analysis was performed at 72 h posttransfection to measure MACC1 protein level. *p < 0.05 compared with miR-NC. #p < 0.05 compared with miR-598 mimics + pCMV-MACC1. (B) MTT and (C) Matrigel invasion assays were applied to detect cell proliferation and invasion. *p < 0.05 compared with miR-NC. #p < 0.05 compared with miR-598 mimics + pCMV-MACC1.