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. 2018 Jul 5;26(6):977–985. doi: 10.3727/096504017X15037506066252

Figure 1.

Figure 1

Overexpression and suppression of miR-34a-5p and their effects on cell viability, migration, invasion, and apoptosis in HeLa cells. (A) Overexpression and suppression of miR-34a-5p in HeLa cells. NC: negative control. (B) Suppression of miR-34a-5p promoted cell viability, while overexpression of miR-34a-5p inhibited cell viability. (C) Suppression of miR-34a-5p promoted migration, while overexpression of miR-34a-5p inhibited migration. (D) Suppression of miR-34a-5p promoted cell invasion, while overexpression of miR-34a-5p inhibited cell invasion. (E) Overexpression of miR-34a-5p induced cell apoptosis. (F) Overexpression of miR-34a-5p enhanced the expression levels of Bax, cleaved caspase3, and cleaved caspase 9 in HeLa cells. GAPDH was used as the loading control. *p < 0.05; **p < 0.01; ***p < 0.001.