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. 2018 Jul 5;26(6):977–985. doi: 10.3727/096504017X15037506066252

Figure 5.

Figure 5

The effects of Bcl-2 on the PI3K/AKT and JAK/STAT signaling pathways in HeLa cells. (A) Overexpression of Bcl-2 activated the PI3K/AKT signaling pathway, while silencing of Bcl-2 inactivated the PI3K/AKT signaling pathway in HeLa cells. (B) Overexpression of Bcl-2 activated the JAK/STAT signaling pathway, while silencing of Bcl-2 inactivated the JAK/STAT signaling pathway in HeLa cells. PI3K, phosphatidylinositide 3-kinase; AKT, serine/threonine-specific protein kinase; JAK, Janus kinase; STAT, signal transducers and activators of transcription.