Figure 1.

Phenotypic characteristics of KKU-214L5 and its parental cells (KKU-214). (A) KKU-214L5 cells exhibited spindle-like shapes (arrows), while KKU-214 cells are polygonal shapes (phase contrast, scale bar: 100 μm). (B) KKU-214L5 cells had no significant growth differences but significantly higher migration and invasion capabilities than the parental KKU-214 cells as shown by the (C) wound healing, (D) migration, and (E) invasion Boyden chamber assays. The data are means ± SD of two independent experiments. **p < 0.01, Student’s t-test.