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. 2018 Oct 17;26(9):1327–1334. doi: 10.3727/096504018X15165493852990

Figure 4.

Figure 4

miR-18a promoted HCC cell proliferation and migration by targeting IRF2 and CBX7. (A) Expression of IRF2 was measured by Western blot assay in the Bel-7402 cell line transfected with or without an IRF2 plasmid. (B) Expression of CBX7 was measured by Western blot assay in Bel-7402 cells transfected with or without a CBX7 plasmid. (C) Cell proliferation was measured in the Bel-7402 cell line after miR-18a mimic or IRF2 plasmid transfection by MTT assay. (D) Cell proliferation was measured in the Bel-7402 cell line after miR-18a mimic or CBX7 plasmid transfection using MTT assay. (E) Cell migration was measured in the Bel-7402 cell line after miR-18a mimic or IRF2 plasmid transfection by the wound healing assay. (F) Cell migration was measured in the Bel-7402 cell line after miR-18a mimic or CBX7 plasmid transfection by wound healing assay. ***p < 0.001, **p < 0.01, *p < 0.05.