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. 2018 Jun 11;26(5):703–712. doi: 10.3727/096504017X14982569377511

Figure 4.

Figure 4

Validation of inositol polyphosphate-5-phosphatase A (INPP5A) as a target of miR-181a-5p. (A) The Dual-Luciferase Reporter Assay in HeLa cells after transfection of mimics and/or INPP5A wild-type (WT) or mutant (mut) 3′-untranslated region (3′-UTR). The mRNA (B) and protein (C) expression of INPP5A in transfected cervical cancer cell lines HeLa and SiHa and normal cervical epithelial End1/E6E7 cells as determined by polymerase chain reaction (PCR) and Western blotting, respectively. *p < 0.05, **p < 0.01.