Figure 5.
Exogenous application of recombinant human TG2 protein augments cell migration and invasion. (A) Culture medium (conditioned medium) collected from CL1-0, CL1-0/TG2, and CL1-5 was analyzed by immunoblotting for TG2. (B, C) CL1-0 cells were untreated or treated with 1 or 2 μg/ml recombinant TG2 protein and subjected to migration assay (B) and invasion assay (C). (B, C) Data are expressed as fold change relative to untreated CL1-0. *p < 0.05, **p < 0.01, ***p < 0.005, compared with untreated CL1-0; ns, not significant.