Figure 4.

Inhibition of miR-188 promotes cell proliferation in glioma LN229 cells. (A) MTT assay showed that anti-miR-188 increased the cell activity at 3 days. (B) Cell cycle analysis showed the percentage of cells in the G₁/G₀, S, and G₂/M phases. S and G₂/M phase cells significantly increased in the anti-miR-188 group. (C) The data showed the percentage of early and late apoptosis in the anti-miR-188 group. (D) c-Myc and cyclin D1 protein expressions were examined in the anti-miR-188 group. *p < 0.01, compared with the anti-miR-Ctrl group, n = 3.