Figure 5.

KRAS promoted cell proliferation, migration, and invasion in T24 cells. Human bladder cancer T24 cells were transfected with pEX-KRAS and sh-KRAS. (A) Expression levels of KRAS stably overexpressed or suppressed in T24 cells were detected by qRT-PCR. (B) Cell viability, (C) migration, (D) invasion, (E) apoptosis, and (F) apoptosis-associated factors were examined by trypan blue exclusion, Transwell assay, flow cytometry, and Western blot, respectively. *p < 0.05, **p < 0.01, ***p < 0.001.