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. Author manuscript; available in PMC: 2021 Aug 1.
Published in final edited form as: Environ Res. 2020 May 21;187:109707. doi: 10.1016/j.envres.2020.109707

Figure 2. Associations between weekly PM2.5 levels over gestation and newborn relative leukocyte telomere length (rLTL).

Figure 2.

This figure demonstrates the association between PM2.5 exposures over pregnancy and rLTL using a BDLIM assuming week-specific effects for the overall sample. The model was adjusted for maternal age, self-reported ethnicity, marital status, education level, maternal lifetime stress, antioxidant intake and infant sex. The y-axis represents the change in rLTL per 1 μg/m3 increase in PM2.5. The x-axis represents gestational age in weeks. The solid line shows the estimated change in rLTL while gray areas indicate 95% credible intervals (CIs). A sensitive window is identified for weeks 12-20 of gestation, where the estimated pointwise 95% CI does not include zero. BDLIMs also identified a cumulative estimated effect of PM2.5 over pregnancy on rLTL of −0.29 (95% CI −0.49 to −0.10) per 1μg/m3 increase in PM2.5.