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. 2018 May 7;26(4):547–556. doi: 10.3727/096504017X15016337254605

Figure 2.

Figure 2

miR-449a upregulation promoted IR sensibility in lung cancer cells. (A, B) A549 and H1299 cells were transfected with miR-449a mimics, and miR-449a level was examined. (C, D) A549 and H1299 cells were transfected with miR-449a mimics or NC and exposed to IR at 8 Gy, and cell viability within 48 h was determined using MTT assay. *p < 0.05, **p < 0.01, versus Control + 8 Gy. (E, F) Soft agar colony formation assay of A549 and H1299 cells transfected with miR-449a mimics or NC for 2 weeks (n = 3). Average number of colonies and representative images are shown. All experiments were repeated at least three times.