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. 2018 Oct 17;26(9):1317–1326. doi: 10.3727/096504018X15179680859017

Figure 5.

Figure 5

Restored Notch1 expression rescues the suppressive effects of miR-708 on gastric cancer cell proliferation and invasion. BGC-823 and SGC-7901 cells were transfected with miR-708 mimics together with pcDNA3.1 or pcDNA3.1-Notch1. (A) After transfection for 72 h, Western blot analysis was conducted to detect Notch1 protein expression. *p < 0.05 compared with miR-NC. #p < 0.05 compared with miR-708 mimics + pcDNA3.1-Notch1. (B) MTT and (C) Matrigel invasion assays were employed to determine cell proliferation and invasion in the above different treated cells. *p < 0.05 compared with miR-NC. #p < 0.05 compared with miR-708 mimics + pcDNA3.1-Notch1.