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. 2018 May 7;26(4):519–528. doi: 10.3727/096504017X15000757094686

Figure 2.

Figure 2

miR-103 inhibits cell proliferation and migration of the A549 cell line. A549 cells were transfected with the negative control mimic (NC) or the miR-103 mimic/NC or the miR-103 inhibitor. miR-103 expression was determined by qRT-PCR (A, B), and cell proliferation was determined by the cell counting kit-8 (CCK-8) assay kit. (C, D). The apoptosis distributions of A549 cells transfected with NC or the miR-103 mimic/NC or the miR-103 inhibitor for 48 h, which was detected by flow cytometry (E, G) and expressed as fold increase versus control (F, H). (I–L) Forty-eight hours after the transfection with NC or the miR-103 mimic/NC or the miR-103 inhibitor, wound healing assays and Transwell assays were performed in A549 cells. n = 3–4 independent experiments. Error bars represent the mean ± SEM. *p < 0.05, compared with control.