Table 2.
Algorithm performance analysis: diagnostic sensitivity and specificity comparing the results reported by an expert (reference) versus by the VETSCAN IMAGYST scanner and algorithm for samples prepared with the VETSCAN IMAGYST centrifugal flotation method
Feline Ancylostoma | Toxocara cati | Cystoisospora | Giardia | |
---|---|---|---|---|
True positive | 19 | 32 | 26 | 25 |
False positive | 1 | 0 | 12 | 2 |
True negative | 60 | 46 | 161 | 65 |
False negative | 0 | 2 | 1 | 8 |
Total | 80 | 80 | 200 | 100 |
Sensitivity (95% confidence interval) | 100 (87.8–100) | 94.1 (82.4–98.8) | 96.3 (84.0–99.6) | 75.8 (59.4–87.8)a |
Specificity (95% confidence interval) | 98.4 (92.6–99.8) | 100 (94.7–100) | 93.1 (88.6–96.2) | 97.0 (90.8–99.4) |
aThirty-six percent (12/33) of Giardia samples contained ≤ 10 cysts per gram (CPG); diagnostic sensitivity of Giardia samples with > 10 CPG increased to 95.2% (95% confidence interval: 79.8-99.5%)