Table 2.
Algorithm performance analysis: diagnostic sensitivity and specificity comparing the results reported by an expert (reference) versus by the VETSCAN IMAGYST scanner and algorithm for samples prepared with the VETSCAN IMAGYST centrifugal flotation method
| Feline Ancylostoma | Toxocara cati | Cystoisospora | Giardia | |
|---|---|---|---|---|
| True positive | 19 | 32 | 26 | 25 |
| False positive | 1 | 0 | 12 | 2 |
| True negative | 60 | 46 | 161 | 65 |
| False negative | 0 | 2 | 1 | 8 |
| Total | 80 | 80 | 200 | 100 |
| Sensitivity (95% confidence interval) | 100 (87.8–100) | 94.1 (82.4–98.8) | 96.3 (84.0–99.6) | 75.8 (59.4–87.8)a |
| Specificity (95% confidence interval) | 98.4 (92.6–99.8) | 100 (94.7–100) | 93.1 (88.6–96.2) | 97.0 (90.8–99.4) |
aThirty-six percent (12/33) of Giardia samples contained ≤ 10 cysts per gram (CPG); diagnostic sensitivity of Giardia samples with > 10 CPG increased to 95.2% (95% confidence interval: 79.8-99.5%)