Table 1.
Entities | ||
Protein | 21,759 | |
Mutation | 490,245 | |
Interface | 72,953 | |
Non-interface | 417,292 | |
Mutation case | 544,692 | |
Interface | 85,484 | |
Non-interface | 459,208 | |
PPI | 121,172 from 3 sources: | |
PDB | 4112 | |
Interactome3D | 2891 | |
ECLAIR | 114,169 | |
Functional site | 535,182 in 8 types: | |
Acetylation | 43,764 | |
Malonylation | 4476 | |
Methylation | 14,649 | |
O-linked glycosylation | 4228 | |
Phosphorylation | 276,738 | |
Succinylation | 1665 | |
Ubiquitination | 100,246 | |
Ligand binding | 89,416 | |
TCGA | 11,315 cases in 33 cancer types | |
Drug | 251 | |
PDB | 41,843 | |
95,599 PDB chains for 6583 proteins | ||
20,132 PDBs for 9589 PPI | ||
5126 PDBs for 6482 PPI (hetero) | ||
17,595 PDBs for 3107 PPI (homo) | ||
Relations | ||
PPI (edgetic) | Protein functional site (nodetic) | |
Mutation | 775,524 mapped interface mutations | 450,685 mapped mutations |
Cancer |
7285 survival analyses 2,087,382 oncoPPI tests |
1599 survival analyses |
Drug | 252,275 drug responses | 1,018,857 drug responses |
PPI protein-protein interaction, Hetero PPI PPI consisting of different proteins, Homo PPI PPI of the same protein