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. 2021 Jan 27;153(2):e202012687. doi: 10.1085/jgp.202012687

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© 2021 Fortenbach et al.

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Figure 9. — Light suppression of the undershoot of K_v2.1^−/− rod photoresponses reveals it to arise from CNG channel current. (A) Paired-flash paradigm: the response of the rod to a single saturating flash (black trace); response of the same rod to a pair of identical flashes (red trace), with the second delivered during the undershoot of the response to the first flash. The ordinate scale is normalized by the saturating amplitude of the photocurrent response to the first flash. (B) Bar chart summarizing results from 10 experiments. The red filled region gives the magnitudes of saturating photocurrents to the first and second flashes in the paired-flash experiment; the gray-filled region stacked on the first flash plots the magnitude of the undershoot. All magnitudes are scaled by the amplitude of the response to the first flash, as in A. The magnitude of the photocurrent response to the second flash is indistinguishable from the sum of the magnitudes of the initial photocurrent and its undershoot.