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. 2021 Jan 19;17(1):e1008594. doi: 10.1371/journal.ppat.1008594

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© 2021 Santiago et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 8 — Junction sequences marking the genomic aberration in U003-C were detected in all 4 other tumors tested, while intact K8.1 sequences were detected in only 2. The cartoon shows the breakpoints in the K8.1 intron of U003-C extending into TR sequences, along with PCR primers used to confirm the genome structure. PCR products from other tumors of participant U003 and from the BCBL-1 cell line are shown at the bottom of the figure. All visible bands were excised from the agarose gel and their structures confirmed by Sanger sequencing.