Table 1. Origin and processing results from specimens for KSHV genome analysis.
Pt ID | Age | Sex | Plasma HIV RNA (copies/mL) | CD4 T cells /μL | Sample ID | Sample Type | % on-target | Median read coverage | Standard Deviation | Median dUMI-consensus read coverage | Standard Deviation | Genome length (excluding masked repeats) | # positions with variants | Mean frequency of variant base | Genbank Accession | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Pre-enrichment | Post-enrichment | |||||||||||||||
n/a | n/a | n/a | n/a | n/a | BCBL-1 | cell line | 0.0009% | 15.61% | 16,805 | 1,858 | 302 | 52.49 | 132,676 | 81 | 1.35% | MT936340 |
U003 | 25 | M | 759,635 | 45 | U003-C | Tumor | 0.0037% | 7.15% | 16,265 | 1,715 | 270 | 30.47 | 131,292 | 21 | 1.80% | MT510648 |
U003-o1 | Oral swab | 0.0000% | 35.20% | 49,598 | 26,446 | 7 | 6.22 | 131,102 | 12 | - | MT510649 | |||||
U003-o2 | Oral swab | 0.0003% | 31.60% | 66,527 | 13,995 | 310 | 68.48 | 131,129 | 218 | 0.51% | MT510650 | |||||
U003-o3 | Oral swab | 0.0000% | 41.90% | 65,984 | 21,979 | 47 | 21.31 | 131,143 | 24 | - | MT510651 | |||||
U004 | 37 | M | 277,655 | 85 | U004-C | Tumor | 0.0016% | 17.20% | 19,582 | 3,078 | 34 | 7.41 | 131,277 | 12 | - | MT510663 |
U004-D | Tumor | 0.0017% | 75.10% | 60,340 | 10,253 | 1,291 | 280.27 | 131,237 | 73 | 0.73% | MT510665 | |||||
U004-o1 | Oral swab | 0.0001% | 18.90% | 37,794 | 6,280 | 56 | 11.70 | 131,277 | 31 | - | MT510664 | |||||
U007 | 26 | M | 91,096 | 136 | U007-B | Tumor | 0.0006% | 86.90% | 75,001 | 19,771 | 1,172 | 268.44 | 131,352 | 156 | 0.17% | MT510654 |
U007-o1 | Oral swab | 0.0001% | 27.60% | 43,707 | 6,258 | 206 | 25.54 | 131,126 | 61 | 1.93% | MT510655 | |||||
U008 | 56 | M | 860,937 | 488 | U008-B | Tumor | 0.0049% | 16.97% | 19,309 | 4,168 | 637 | 148.42 | 131,142 | 31 | 0.93% | MT510656 |
U008-D | Tumor | 0.0040% | 29.98% | 26,209 | 4,674 | 195 | 42.95 | 131,102 | 24 | 0.70% | MT510657 | |||||
U008-o1 | Oral swab | 0.0000% | 23.50% | 48,339 | 6,869 | 114 | 16.62 | 131,116 | 76 | 2.11% | MT510658 | |||||
U020 | 27 | M | 118,191 | 370 | U020-B | Tumor | 0.0070% | 1.47% | 2,913 | 14,971 | 24 | 196.60 | 131,102 | 10 | 2.40% | MT510666 |
U020-C | Tumor | 0.0003% | 34.38% | 420 | 3,674 | 3 | 2.51 | 131,471 | 30 | - | MT510667 | |||||
U020-o1 | Oral swab | 0.0000% | 77.30% | 73,287 | 22,429 | 80 | 21.66 | 131,115 | 22 | - | MT510668 | |||||
U023 | 33 | F | 338,285 | 191 | U023-o1 | Oral | 0.0001% | 2.70% | 19,889 | 6,683 | 2 | 1.30 | 131,122 | 2 | - | MT510669 |
U030 | 40 | M | 100,184 | 70 | U030-C | Tumor | 0.0135% | 15.68% | 38,935 | 6,664 | 490 | 62.59 | 131,282 | 17 | 1.08% | MT510670 |
U032 | 23 | F | 587,149 | 274 | U032-B | Tumor | 0.0003% | 43.50% | 69,815 | 9,269 | 890 | 67.12 | 131,266 | 45 | 0.41% | MT510652 |
U032-o1 | Oral | 0.0000% | 7.70% | 7,311 | 3,218 | 1 | 0.80 | 130,842 | - | - | MT510653 | |||||
U034 | 47 | F | 130,375 | 237 | U034-B | Tumor | 0.0014% | 84.40% | 74,927 | 13,969 | 1,747 | 189.51 | 131,248 | 107 | 0.11% | MT510659 |
U034-C | Tumor | 0.0013% | 30.70% | 17,968 | 2,505 | 133 | 24.36 | 131,088 | 11 | 1.46% | MT510660 | |||||
U034-o1 | Oral swab | 0.0000% | 7.30% | 7,851 | 2,818 | 2 | 1.22 | 130,754 | 2 | - | MT510661 | |||||
U034-o2 | Oral swab | 0.0000% | 6.00% | 4,085 | 1,735 | 1 | 0.62 | 130,884 | - | - | MT510662 |