Skip to main content
. 2021 Jan 29;16(1):e0245747. doi: 10.1371/journal.pone.0245747

Table 2. Adjusted binary logistic regression analyses showing the relationship between total number of life stress events and risk for infection-related hospitalisations in childhood (N = 2,141, age 0–16).

Adjusted odds ratio for any hospital admission (95% confidence interval)
Any infection LRTI URTI GI Other
Life stress events
Both (n = 2141) 1.04 (0.99, 1.08) 1.05 (0.98, 1.12) 1.03 (0.98, 1.08) 1.09 (1.02, 1.17) 1.09 (1.03, 1.16)
Male (n = 1121) 1.08 (1.02, 1.14) 1.12 (1.03, 1.22) 1.07 (1.00, 1.14) 1.12 (1.02, 1.23) 1.17 (1.08, 1.28)
Female (n = 1020) 0.99 (0.93, 1.05) 0.96 (0.87, 1.07) 0.99 (0.92, 1.06) 1.05 (0.95, 1.17) 1.01 (0.92, 1.10)
Timing of stress events ≤ 18 weeks’ gestation only
Both 0.97 (0.74, 1.28) 0.66 (0.40, 1.08) 1.03 (0.76, 1.40) 1.10 (0.65, 1.86) 0.95 (0.60, 1.49)
Male 1.16 (0.79, 1.69) 0.89 (0.44, 1.76) 1.06 (0.68, 1.65) 1.45 (0.66, 3.18) 1.23 (0.59, 2.56)
Female 0.80 (0.54, 1.18) 0.48 (0.24, 0.98) 0.99 (0.64, 1.52) 0.88 (0.43, 1.78) 0.81 (0.45, 1.44)
18–34 weeks’ gestation only
Both 1.02 (0.76, 1.37) 1.09 (0.67, 1.76) 0.90 (0.63, 1.27) 1.63 (0.96, 2.76) 0.86 (0.51, 1.43)
Male 1.29 (0.85, 1.96) 1.42 (0.71, 2.83) 0.94 (0.56, 1.55) 2.02 (0.90, 4.53) 1.36 (0.61, 3.01)
Female 0.77 (0.50, 1.18) 0.81 (0.41, 1.62) 0.84 (0.52, 1.36) 1.33 (0.66, 2.68) 0.61 (0.31, 1.21)
Both 18 and 34 weeks’ gestation
Both 1.10 (0.88, 1.38) 0.97 (0.66, 1.40) 1.03 (0.80, 1.33) 1.29 (0.84, 1.98) 1.26 (0.88, 1.81)
Male 1.54 (1.13, 2.11) 1.25 (0.73, 2.15) 1.20 (0.83, 1.73) 2.04 (1.06, 3.92) 2.11 (1.17, 3.82)
Female 0.75 (0.54, 1.05) 0.73 (0.43, 1.22) 0.88 (0.61, 1.26) 0.79 (0.44, 1.43) 0.84 (0.52, 1.35)

odds ratio and 95% confidence intervals. Model adjusted for maternal age at pregnancy, maternal education at pregnancy and maternal smoking in pregnancy. LRTI: Lower respiratory tract infection; URTI: Upper respiratory tract infection; GI: Gastrointestinal infection; Other: Genitourinary infection, skin and soft tissue infection or other viral infection.