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. 2021 Jan 29;16(1):e0246182. doi: 10.1371/journal.pone.0246182

Table 2. Fatal outcome and survival in ARDS and non ARDS patients.

ARDS   non ARDS
Survivor (N = 33) Non-Survivor (N = 26) P value Survivor (N = 54) Non-Survivor (N = 12) P value
Characteristics
Age 63.1 [60.0–66.2] 66.2 [62.1–70.2] 0.102 65.4 [60.8–70.0] 78.8 [73.1–84.4] <0.012
Female Sex 11 (33.3%) 10 (38.5%) 0.681 15 (27.8%) 2 (16.7%) 0.431
Symptom onset to Hospitalisation 7.0 [5.0–9.1] 5.2 [2.7–7.7] 0.092 5.5 [4.0–6.9] 2.4 [0.0–4.8] 0.042
BMI 29.9 [28.2–31.7] 31.3 [28.2–34.5] 0.832 28.2 [26.6–29.8] 25.4 [22.3–28.5] 0.202
Comorbidities
Total 32 (97.0%) 25 (96.2%) 0.861 51 (94.4%) 12 (100.0%) 0.401
Arterial hypertension 21 (63.6%) 21 (80.8%) 0.151 37 (68.5%) 11 (91.7%) 0.101
Pre-existing respiratory disease 13 (39.4%) 11 (42.3%) 0.821 24 (44.4%) 6 (50.0%) 0.731
Pre-existing heart disease 10 (30.3%) 14 (53.8%) 0.071 22 (40.7%) 5 (41.7%) 0.951
Overweight (BMI = 25 kg/m2, < 30 kg/m2) 14 (42.4%) 8 (30.8%) 0.361 17 (34.0%) 3 (27.3%) 0.671
Obesity (BMI = 30 kg/m2) 15 (45.5%) 12 (46.2%) 0.961 15 (30.0%) 2 (18.2%) 0.431
Chronic kidney disease 6 (18.2%) 7 (26.9%) 0.421 18 (33.3%) 5 (41.7%) 0.581
Smoking 7 (35.0%) 4 (30.8%) 0.801 20 (64.5%) 3 (50.0%) 0.501
Former smoking 2 (10.0%) 2 (15.4%) 0.641 8 (25.8%) 3 (50.0%) 0.241
Current smoking 5 (25.0%) 2 (15.4%) 0.511 12 (38.7%) 0 (0.0%) 0.061
Diabetes mellitus 4 (12.1%) 9 (34.6%) 0.041 15 (27.8%) 3 (27.3%) 0.971
Malignancy 6 (18.2%) 5 (19.2%) 0.921 14 (26.4%) 5 (41.7%) 0.291
Chronic liver failure 0 (0.0%) 0 (0.0%) - 0 (0.0%) 0 (0.0%) -
Chronic hepatitis 0 (0.0%) 1 (3.8%) 0.261 5 (9.3%) 0 (0.0%) 0.271
Peripheral arterial occlusive disease 2 (6.1%) 2 (7.7%) 0.801 3 (5.6%) 1 (8.3%) 0.721

Numeric parameters are expressed as median [95%CI], categorical as N(%).

1Pearson chi-squared.

2Mann-Whitney-U. ARDS = acute respiratory distress syndrome. BMI = body mass index.