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. 2021 Jan 29;16(1):e0246182. doi: 10.1371/journal.pone.0246182

Table 3. Microbiological findings of the different subgroups.

  N/N total (%)   N/N total (%)  
  All patients (N = 125) ARDS patients (N = 59) non-ARDS patients (N = 66) P values Non-Survivors (N = 38) Survivors (N = 87) P values
Viral load              
High 22/113 (19) 10/52 (19) 12/61 (20) >0.99 7/37 (19) 15/76 (20) >0.99
Medium 66/113 (58) 32/52 (62) 34/61 (56) 0.57 24/37 (65) 42/76 (55) 0.54
Low 25/113 (22) 10/52 (19) 15/61 (25) 0.64 6/37 (16) 19/76 (25) 0.33
Ct S-Gen—Median (IQR) 25.6 (20.7–29.4) 25.6 (20.7–29.3) 25.2 (20.2–29.7) 0.60 25,5 (20,8–29,4) 25,6 (20,6–29,4) 0.88
Viral detection
Pulmonary manifestation 107/123 (87) 46/58 (79) 61/65 (94) 0.02 34/38 (89) 73/85 (86) 0.77
    positive out of hospital 18 (14) 11 (31) 7 (27) - 3 (8) 15 (17) -
Extrapulmonary manifestation 40/95 (42) 27/53 (51) 13/42 (31) 0.06 18/26 (69) 18/66 (27) 0.002
    Serum 27/71 (38) 21/35 (60) 6/36 (17) 0.0002 12/20 (60) 15/51 (29) 0.02
    Stool 13/40 (33) 6/20 (30) 7/20 (35) >0.99 6/10 (60) 7/30 (23) 0.05
    Urine 12/63 (19) 7/36 (19) 5/27 (19) >0.99 7/20 (35) 5/43 (12) 0.03
Bacterial detection
Blood culture 24/109 (22) 19/58 (33) 5/51 (10) 0.005 10/36 (28) 15/73 (21) 0.46
Urine culture 47/99 (47) 26/53 (49) 21/46 (46) 0.84 13/31 (42) 35/69 (51) 0.51

Data in N/N total (%) or Median (IQR). In ordinal scaled parameters testing for normal distribution and calculation of P values with Welch test or Wilcoxon-Mann-Whitney test. P values of nominal scaled parameter calculated with Fisher’s exact test. SEM = standard error of the mean. ARDS = acute respiratory distress syndrome. IQR = interquartile range. Ct = cyclic threshold.