Table 8. mtDNA heteroplasmy 23 hot-spots found in blood of 222 subjects.

SNP Change	Total SNPs (n = 222)	Young Normal (n = 83)	Older Normal (n = 66)	Older AMD (n = 73)
1120 C>T	219	82 (98.8%)	64 (97%)	73 (100%)
1284 T>C	218	82 (98.8%)	64 (97%)	72 (98.6%)
1556 C>T	218	82 (98.8%)	64 (97%)	72 (98.6%)
4104 A>G	187	82 (98.8%)	50 (75.8%)	55 (75.3%)
4556C>T	0	0	0	0
5320C>T	185	78 (93.4%)	51 (77.3%)	56 (76.7%)
5471G>A	170	78 (93.4%)	44 (66.7%)	48 (65.8%)
5474A>G	170	78 (93.4%)	44 (66.7%)	48 (65.8%)
5498A>G	156	74 (89.2%)	37 (56.1%)	45 (61.6%)
5840 C>T	194	77 (92.8%)	54 (81.8%)	63 (86.3%)
6023 G>A	198	78 (94%)	55 (83.3%)	65 (89%)
7146 A>G	197	78 (94%)	56 (81.8%)	63 (86.3%)
7256 C>T	216	81 (97.6%)	64 (97%)	71 (97.2%)
9075 C>T	198	78 (94%)	55 (83.3%)	65 (89%)
9168 C>T	196	78 (94%)	54 (81.8%)	64 (87.7%)
9254 A>G	192	78 (94%)	51 (77.3%)	63 (86.3%)
9629 A>G	192	78 (94%)	52 (77.3%)	62 (84.9%)
11914G>A	188	75 (90.4%)	51 (77.3%)	62 (84.9%)
12705 C>T	182	69 (83.1%)	50 (75.8%)	63 (86.3%)
13095 T>C	165	56 (67.5%)	47 (71.2%)	62 (84.9%)
13105 A>G	166	57 (68.7%)	46 (69.7%)	63 (86.3%)