Table 3. Comparison of viral RNA load at different time points between groups.
Control group | HCQ group | Mann-Whitney U Test | ||||
---|---|---|---|---|---|---|
n | median IQR[Q2;Q3] | n | median IQR[Q2;Q3] | p-value unadj | q-value | |
Day 0, total RNA copies in swab | 12 | 447 847 [23 821;1 030 282] | 33 | 130 183 [33 812;982 481] | 0.38 | 0.45 |
Day 3, total RNA copies in swab | 12 | 27 638.5 [20 138;45 794] | 29 | 27 715.0 [17 204;87 433] | 0.45 | 0.45 |
Day 8, total RNA copies in swab | 10 | 19 001.5 [0;28 313] | 26 | 23 880.5 [8 094;36 859] | 0.18 | 0.45 |
HCQ, hydroxychloroquine; IQR, interquartile range; Q2, quartile 2; Q3, quartile 3. Differences between groups were quantified using the Mann–Whitney U test without (p-value unadj) and with the Benjamini-Hochberg correction (q-value).