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. 2021 Jan 29;16(1):e0246396. doi: 10.1371/journal.pone.0246396

Table 3. Comparison of viral RNA load at different time points between groups.

Control group HCQ group Mann-Whitney U Test
n median IQR[Q2;Q3] n median IQR[Q2;Q3] p-value unadj q-value
Day 0, total RNA copies in swab 12 447 847 [23 821;1 030 282] 33 130 183 [33 812;982 481] 0.38 0.45
Day 3, total RNA copies in swab 12 27 638.5 [20 138;45 794] 29 27 715.0 [17 204;87 433] 0.45 0.45
Day 8, total RNA copies in swab 10 19 001.5 [0;28 313] 26 23 880.5 [8 094;36 859] 0.18 0.45

HCQ, hydroxychloroquine; IQR, interquartile range; Q2, quartile 2; Q3, quartile 3. Differences between groups were quantified using the Mann–Whitney U test without (p-value unadj) and with the Benjamini-Hochberg correction (q-value).