Table 2.

Effect of E-Cigarette Liquids and Nicotine on Oxidative Stress of Oral Epithelial Cell Lines Detected by the ROS-Glo Assay

E-Liquid a	Cell Lines
	MOE1A		MOE1B		MSK1
	(–)	(+)	(–)	(+)	(–)	(+)
			(Maximum Significant Fold Change)
Unflavored	NS	NS	NS	NS	NS	NS
Arctic Blast	NS	NS	NS	1.3	NS	NS
Blue Pucker	1.2	2.3	NS	1.6	NS	16
Jamestown	NS	NS	NS	1.3	NS	NS
Love Potion	NS	1.9*	1.8	1.9*	1.5	1.8*
Mardi Gras	1.2	NS	NS	1.5	1.3	1.3
Midnight Splash	1.2	NS	1.5*	NS	NS	NS
Port Royale	1.9	NS	2.4*	NS	1.5*	NS
Tobacco Row	1.2	NS	NS	1.3	1.2	1.5
Tortuga	1.3	1.2	1.4	1.1	1.2	NS
Uptown	NS	NS	NS	NS	NS	1.3
Kentucky reference cigarette 3R4F	2.2*		1.5*		2.0*

Abbreviations: (–), no nicotine; (+), nicotine; NS, not significant.

^aAll e-liquids contain 70%PG/30% VG.

^* p < .05 for dose response trend test.