Table 3.
Pathway analysis performed with the DAVID v6.8 using a list of DEGs for liver abscesses
| Term | Count | P-value | Genes1 |
|---|---|---|---|
| Transcriptional misregulation in cancer | 6 | 0.02 | IGF1R, RELA, TSPAN7, ETV6, ETV5, HIST1H3G |
| cAMP signaling pathway | 6 | 0.03 | HCN2, ADRB2, ATP1B3, RELA, CREB3L2, SLC9A1 |
| Ribosome | 5 | 0.03 | RPS25, RPL22, RPS27L, RPL38, RPL39 |
| Cardiac muscle contraction | 4 | 0.03 | COX7A1, ATP1B3, SLC9A1, UQCRB |
| NFKB signaling pathway | 4 | 0.05 | LY96, RELA, RELB, TRIM25 |
1 IGF1R, insulin-like growth factor 1 receptor; RELA, RELA proto-oncogene, NFKB subunit; TSPAN7, tetraspanin 7; ETV6, ETS variant transcription factor 6; ETV5, ETS variant transcription factor 5; HIST1H3G, histone H3; HCN2, hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2; ADRB2, adrenoceptor beta 2; ATP1B3, ATPase Na+/K+ transporting subunit beta 3; CREB3L2, CAMP responsive element-binding protein 3 like 2; SCL9A1, sodium/hydrogen exchanger NHE1; RPS25, ribosomal protein S25; RPL22, ribosomal protein L22; RPS27L, ribosomal protein S27 like; RPL38, ribosomal protein L38; RPL39, ribosomal protein L39; COX7A1, cytochrome C oxidase subunit 7A1; UQCRB, ubiquinol-cytochrome C reductase-binding protein; LY96, lymphocyte antigen 96; RELB, RELB proto-oncogene, NFKB subunit; TRIM25, tripartite motif containing 25.