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Summary of Targeted Therapies for Gliomas in Completed or Currently Enrolling Clinical Trials
| Target | Drug | Clinical Trial |
|---|---|---|
| BRAF | Vemurafenib | NCT01524978 |
| RAS/RAF/MEK/ERK | TAK-580 | NCT03429803 |
| Dabrafenib/Trametinib | NCT02034110, NCT02684058 | |
| Encorafenib/Binimetinib | NCT03973918 | |
| EGFR | ABT-414 | NCT01800695 |
| H3 K27M | Panobinostat | NCT02717455 |
| IDH1/2 | Vorasidenib (AG-881) | NCT04164901 |
| VEGF(R) | Bevacizumab | NCT00345163 |
| Regorafenib | NCT03970447 |
