Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jan 29;29(3):489–502.e8. doi: 10.1016/j.chom.2021.01.015

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 Elsevier Inc.

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

PMC Copyright notice

Prevalence of deletion variants in the 500-532 locus in SARS-CoV-2 genome

(A) Percentage of deletion in the SARS-CoV-2 genome. The red arrow indicates the 500-532 locus.

(B) Sashimi plot indicates the sequencing reads that were mapped around the identified Δ500-532 region (see Figures S6B and S6C).

(C) The alignment of amino acid residues of mutation neighboring 500-532 locus in Nsp1 coding region. Identified cases number (N) and the number of countries were shown. WT, wild-type SARS-CoV-2 Nsp1 sequence. Stars indicate the deletion mutants that were further tested experimentally (related to Figures 5, 6, and 7).

(D) The confirmed (left y axis) or accumulated (right y axis) cases with Nsp1 deletion mutants. The pie chart shows the percentages of cases identified in each continent.

(E) Geographic distribution of COVID-19 cases with the deletion variants worldwide. Color intensity on the map indicates confirmed cases in that region. The pie charts indicate the proportions of different deletion variants in each country, and the size of pie charts indicate the number of cases with the deletion mutants.