Fig. 2.

Combination of heparin-binding protein (HBP) and interleukin (IL)-6 for the prognostication of the development of severe respiratory failure (SRF). (a) HBP admission concentrations among patients who will become in need or who will not become in need of mechanical ventilation (MV). The p value of comparison by the Mann-Whitney U test is provided. Circles denote outliers, and asterisk denotes extremes. (b) IL-6 admission concentrations among patients who will become or who will not become in need of mechanical ventilation (MV). The p value of comparison by the Mann-Whitney U test is provided. Circles denote outliers, and asterisk denotes extremes. (c) Risk of development of SRF among patients without any increase of admission HBP and IL-6, among patients with increase of only IL-6 or HBP, and among patients with increase of both HBP and IL-6. The p values of significance of the indicated comparisons are provided