Table 1.

Comparison of healthy donors, patients with COVID-19 (without or with ARDS), and patients with ARDS unrelated to COVID-19

Index	ARDS		P*	non-ARDS		P*
	No COVID-19	COVID-19		COVID-19	Healthy donors
No. of patients	8	9		11	10
Sex
Female	2	4		6	5
Male	6	5		5	5
Survivors	7	9		11	10
Age, y	57 ± 23.98	57 ± 24.04	>.99	47.54 ± 13.99	45.40 ± 18.58	.7674
Weight, kg	85.43 ± 22.40	71.17 ± 16.70	.2219	71.36 ± 10.75	74.00 ± 15.64	.6546
Hospitalization time, d	9.14 ± 5.96	12 ± 4.53	.2930	9.00 ± 3.07	0 + 0	NA
Mechanical ventilation	Yes	Yes	NA	No	No	NA
FiO2, %	50 ± 20	62.86 ± 7.56	.1463	NA	NA	NA
PaO2:FiO2, mm Hg	<150	<150	NA	NA	NA	NA
Values at admission
Platelet count, × 109/L	243.0 ± 74.4	159.9 ± 76.51	.0467	194.55 ± 82.07	273.20 ± 64.27	.0253
Lymphocyte count, × 109/L	2.13 ± 1.032	1.28 ± 0.6438	.0621	1.27 ± 0.76	2.15 ± 1.20	.0568
Platelet:lymphocyte ratio	144 ± 92.06	141.2 ± 72.24	.9465	165.24 ± 53.39	177.82 ± 124.41	.7627
ALT, U/L	34.94 ± 15.61	33.27 ± 13.61	.1016	34.11 ± 15.56	16.74 ± 5.88	.0036
AST, U/L	35.43 ± 12.05	42.98 ± 10.74	.2069	35.11 ± 17.82	15.95 ± 3.93	.0036
LDH, U/L	417.9 ± 202.4	649.1 ± 245.6	.0639	583.27 ± 258.68	314.80 ± 110.45	.0068
C-reactive protein, mg/L	16.16 ± 8.79	18.52 ± 13.67	.6989	13.78 ± 7.99	8.16 ± 3.82	.0576
D-dimers, mg/L	0.39 ± 0.29	1.31 ± 0.57	.0017	0.97 ± 0.54	0.40 ± 0.28	.0076
Fibrinogen, mg/dL	260.62 ± 92.49	439.50 ± 76.29	.0005	274.64 ± 102.02	272.70 ±76.31	.9615

Data are presented as mean ± standard deviation.

ALT, alanine aminotransferase; AST, aspartate aminotransferase; LDH, lactate dehydrogenase; NA, not applicable.

^*Statistical analysis: unpaired Student t test was used to calculate P values.