Table 3.
Random Forest performance testing for detecting AD patients ( test dataset;10% of the original data).
| Modalities | Precision (%) | Recall (%) | MCA (%) | MCF (%) | ||||
|---|---|---|---|---|---|---|---|---|
| CN | MCI | AD | CN | MCI | AD | |||
| All modalities | 100.0 | 86.54 | 96.30 | 86.67 | 97.83 | 89.66 | 92.38 | 92.81 |
| CS | 100.0 | 71.43 | 93.75 | 86.61 | 97.83 | 51.72 | 81.90 | 83.29 |
| NB | 85.29 | 81.63 | 95.45 | 96.60 | 86.96 | 72.41 | 85.71 | 86.39 |
| MRI | 50.31 | 48.28 | 72.22 | 40.01 | 91.30 | 44.83 | 52.38 | 42.61 |
| PET | 50.00 | 55.22 | 73.53 | 36.67 | 80.43 | 86.21 | 60.95 | 58.66 |
| Genetics | 66.67 | 49.28 | 40.21 | 80.00 | 73.91 | 35.33 | 55.24 | 44.09 |
| MH | 33.33 | 52.54 | 38.46 | 36.67 | 67.39 | 17.24 | 44.76 | 40.93 |
| NB + CS | 100.0 | 84.91 | 96.15 | 86.67 | 97.83 | 86.21 | 91.43 | 91.93 |
| NB + MRI | 73.68 | 79.55 | 95.65 | 93.33 | 76.09 | 75.86 | 80.95 | 82.36 |
| NB + PET | 86.21 | 75.93 | 95.45 | 83.33 | 89.13 | 72.41 | 82.86 | 83.69 |
| NB + Genetics | 87.50 | 83.67 | 95.83 | 93.33 | 89.13 | 79.31 | 87.62 | 88.12 |
| NB + MH | 87.50 | 77.36 | 95.00 | 93.33 | 89.13 | 65.52 | 83.81 | 84.59 |
| NB + CS + MRI | 100.0 | 83.64 | 100.0 | 86.67 | 100.0 | 82.76 | 91.43 | 92.12 |
| NB + CS + PET | 100.0 | 82.14 | 100.0 | 86.67 | 100.0 | 79.31 | 90.48 | 91.27 |
| NB + CS + Genetics* | 100.0 | 86.79 | 100.0 | 86.67 | 100.0 | 89.66 | 93.33 | 93.82 |
| NB + CS + MH | 100.0 | 86.54 | 96.30 | 86.67 | 97.83 | 89.66 | 92.38 | 92.81 |
| NB + CS + Genetics + MRI | 100.0 | 85.19 | 100.0 | 86.67 | 100.0 | 86.21 | 92.38 | 92.97 |
| NB + CS + Genetics + PET | 100.0 | 85.19 | 100.0 | 86.67 | 100.0 | 86.21 | 92.38 | 92.97 |
| NB + CS + Genetics + MH | 100.0 | 86.79 | 100.0 | 86.67 | 100.0 | 89.66 | 93.33 | 93.82 |
| NB + CS + Genetics + MH + MRI | 100.0 | 86.54 | 96.30 | 86.67 | 97.83 | 89.66 | 92.38 | 92.81 |
| NB + CS + Genetics + MH + PET | 96.15 | 84.62 | 96.30 | 83.33 | 95.65 | 89.66 | 90.48 | 90.93 |
MCA: multiclass classification accuracy, MCF: multiclass F1 score; Asterisk ( ∗): is the subset of features with the best predictive performance; italic text is the best of single and pairs of modalities.