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. 2021 Jan 29;11:2660. doi: 10.1038/s41598-021-82098-3

Table 3.

Random Forest performance testing for detecting AD patients (MS2 test dataset;10% of the original data).

Modalities Precision (%) Recall (%) MCA (%) MCF (%)
CN MCI AD CN MCI AD
All modalities 100.0 86.54 96.30 86.67 97.83 89.66 92.38 92.81
CS 100.0 71.43 93.75 86.61 97.83 51.72 81.90 83.29
NB 85.29 81.63 95.45 96.60 86.96 72.41 85.71 86.39
MRI 50.31 48.28 72.22 40.01 91.30 44.83 52.38 42.61
PET 50.00 55.22 73.53 36.67 80.43 86.21 60.95 58.66
Genetics 66.67 49.28 40.21 80.00 73.91 35.33 55.24 44.09
MH 33.33 52.54 38.46 36.67 67.39 17.24 44.76 40.93
NB + CS 100.0 84.91 96.15 86.67 97.83 86.21 91.43 91.93
NB + MRI 73.68 79.55 95.65 93.33 76.09 75.86 80.95 82.36
NB + PET 86.21 75.93 95.45 83.33 89.13 72.41 82.86 83.69
NB + Genetics 87.50 83.67 95.83 93.33 89.13 79.31 87.62 88.12
NB + MH 87.50 77.36 95.00 93.33 89.13 65.52 83.81 84.59
NB + CS + MRI 100.0 83.64 100.0 86.67 100.0 82.76 91.43 92.12
NB + CS + PET 100.0 82.14 100.0 86.67 100.0 79.31 90.48 91.27
NB + CS + Genetics* 100.0 86.79 100.0 86.67 100.0 89.66 93.33 93.82
NB + CS + MH 100.0 86.54 96.30 86.67 97.83 89.66 92.38 92.81
NB + CS + Genetics + MRI 100.0 85.19 100.0 86.67 100.0 86.21 92.38 92.97
NB + CS + Genetics + PET 100.0 85.19 100.0 86.67 100.0 86.21 92.38 92.97
NB + CS + Genetics + MH 100.0 86.79 100.0 86.67 100.0 89.66 93.33 93.82
NB + CS + Genetics + MH + MRI 100.0 86.54 96.30 86.67 97.83 89.66 92.38 92.81
NB + CS + Genetics + MH + PET 96.15 84.62 96.30 83.33 95.65 89.66 90.48 90.93

MCA: multiclass classification accuracy, MCF: multiclass F1 score; Asterisk ( ∗): is the subset of features with the best predictive performance; italic text is the best of single and pairs of modalities.