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. 2020 Nov 22;12(1):5–14. doi: 10.1007/s12687-020-00495-z

Table 2.

The frequencies of the 12 most frequent β-thalassemia mutations among 1039 characterized chromosomes among Kurds

Mutation Origin Number of alleles (%) (total 1039)
IVS-II-1 (G>A) Eastern Mediterranean 340 (32.7)
IVS-I-6 (T>C) Mediterranean 182 (17.5)
IVS-I-1 (G>A) Mediterranean 84 (8.1)
Codon 8 (−AA) Turkish 80 (7.7)
Codons 8/9 (+G) Asian Indian 65 (6.3)
IVS-I-110 (G>A) Mediterranean 51 (4.9)
Codon 5 (−CT) Mediterranean 49 (4.7)
Codon 39 (C>T) Western Mediterranean 41 (3.9)
Codon 44 (−C) Kurdish 40 (3.8)
IVS-I-5 (G>C) Asian Indian 25 (2.4)
IVS-I-128 (T>G) Saudi Arabian 20 (1.9)
Codon 82/83 (−G) Azerbaijani 14 (1.3)