Table 4.
The variation in the frequencies of various β-thalassemia mutations in the three main provinces of Kurdistan region
| Mutation | Relative frequency (%) | ||
|---|---|---|---|
| Duhok | Erbil | Sulaimani | |
| IVS-II-1 (G>A) | 18.3 | 28.4 | 25.2 |
| IVS-I-6 (T>C) | 8.7 | 3.4 | 4.1 |
| IVS-I-1 (G>A) | 8.7 | 23.0 | 4.1 |
| Codon 8 (−AA) | 2.9 | 12.8 | 15.4 |
| Codons 8/9 (+G) | 7.7 | 10.1 | 12.2 |
| IVS-I-110 (G>A) | 1.9 | 2.0 | 19.5 |
| Codon 5 (−CT) | 10.6 | 5.4 | 7.3 |
| Codon 39 (C>T) | 8.7 | 4.7 | 1.6 |
| Codon 44 (−C) | 12.5 | 1.3 | 1.6 |
| IVS-I-5 (G>C) | 6.7 | 0.7 | 8.1 |
| Reference | Al-Allawi et al. (2006) | Al-Allawi et al. (2010a) | Jalal et al. (2010) |
| No. of alleles | 104 | 148 | 123 |