Table 5.
The distribution of various α-thalassemia alleles, overall and in the three provinces of Iraqi Kurdistan among 219 individuals with unexplained hypochromia and microcytosis
| Mutation | Number of alleles (%) | |||
|---|---|---|---|---|
| Duhok | Sulaimani | Erbil | Cumulative no. | |
| −α3.7 | 36 (67.9) | 62 (59.6) | 66 (62.9) | 164 (62.6) |
| --MED | 12 (22.6) | 24 (23.1) | 7 (6.7) | 43 (16.4) |
| αPoly A1α | 1(1.9) | 4 (3.8) | 6 (5.7) | 11(4.2) |
| −α4.2 | 2 (3.8) | 2 (1.9) | 2 (1.9) | 6 (2.3) |
| ααAdana | 1 (1.9) | 3 (2.9) | 3 (2.9) | 7 (2.7) |
| −(α)20.5 | - | 3 (2.9) | - | 3 (1.1) |
| α−5ntα | - | 3(2.9) | 21(20) | 24 (9.2) |
| αCSα | - | 2 (1.9) | - | 2 (0.8) |
| αPolyA2α | - | 1 (1.0) | - | 1 (0.4) |
| ααEvanson | 1(1.9) | - | - | 1(0.4) |
| Total no. of alleles characterized | 53 | 104 | 105 | 262 |