Table 3.
Clinical characteristics of patients at the end of follow-up (n = 228).
Mean (standard deviation) or Frequency (%) |
p-value | |||
Variable | Total (n = 228) |
NTP (n = 114; 50%) |
TP (n = 114; 50%) |
|
Digestive form | 15 (6.6) | 9 (7.9) | 6 (5.3) | 0.42 |
Arterial Hypertension | 73 (32.0) | 45 (39.5) | 28 (24.6) | 0.02 |
Diabetes Mellitus | 28 (12.3) | 15 (13.2) | 13 (11.4) | 0.69 |
Dislipidemia | 76 (33.3) | 49 (43.0) | 27 (23.7) | 0.002 |
Non-chagasic cardiomyopathy | 6 (2.6) | 3 (2.6) | 3 (2.6) | 1.00 |
Other comorbidities* | 38 (16.7) | 26 (22.8) | 12 (10.5) | 0.01 |
Clinical presentation of Chagas disease | ||||
Indeterminate | 195 (85.5) | 90 (78.9) | 105 (92.1) | 0.02 |
Cardiac stage A | 23 (10.1) | 16 (14.0) | 7 (6.1) | |
Cardiac stage B1 | 5 (2.2) | 3 (2.6) | 2 (1.8) | |
Cardiac stage B2 | 0 (0.0) | 0 (0.0) | 0 (0.0) | |
Cardiac stage C | 5 (2.2) | 5 (4.4) | 0 (0.0) | |
CD specific ECG abnormalities | 34 (14.9) | 25 (21.9) | 9 (7.9) | 0.003 |
Second or third-degree right bundle-branch block | 14 (6.1) | 11 (9.7) | 3 (2.6) | 0.03 |
Frequent atrial or ventricular premature beats | 5 (2.2) | 3 (2.6) | 2 (1.8) | 0.65 |
Primary ST-T wave abnormalities | 13 (5.7) | 11 (9.7) | 2 (1.8) | 0.01 |
Electrical inactive area | 4 (1.8) | 2 (1.8) | 2 (1.8) | 1.00 |
Second or three-degree left bundle-branch block | 2 (0.9) | 1 (0.9) | 1 (0.9) | 1.00 |
Atrial flutter | 1 (0.4) | 1 (0.9) | 0 (0.0) | 0.32 |
Atrial tachycardia | 1 (0.4) | 1 (0.9) | 0 (0.0) | 0.32 |
Echocardiogram abnormalities (n = 172) | 56 (32.6) | 40 (42.1) | 16 (20.8) | 0.003 |
Diastolic dysfunction | 42 (24.4) | 32 (33.7) | 10 (13.0) | 0.002 |
Segmental dysfunction | 19 (11.1) | 14 (14.8) | 5 (6.5) | 0.09 |
Global systolic dysfunction | 13 (7.6) | 10 (10.5) | 3 (3.9) | 0.10 |
Serological cure | 13 (5.7) | 0 (0.0) | 13 (11.4) | <0.001 |
Other comorbidities included cancer, asthma, chronic obstructive pulmonary disease, hypothyroidism, depression, alcohol abuse, and co-infection (HIV, HTLV, and viral hepatitis).