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. 2020 Dec 23;31:100694. doi: 10.1016/j.eclinm.2020.100694

Table 3.

Clinical characteristics of patients at the end of follow-up (n = 228).

Mean (standard deviation) or Frequency (%)
p-value
Variable Total
(n = 228)
NTP
(n = 114; 50%)
TP
(n = 114; 50%)

Digestive form 15 (6.6) 9 (7.9) 6 (5.3) 0.42
Arterial Hypertension 73 (32.0) 45 (39.5) 28 (24.6) 0.02
Diabetes Mellitus 28 (12.3) 15 (13.2) 13 (11.4) 0.69
Dislipidemia 76 (33.3) 49 (43.0) 27 (23.7) 0.002
Non-chagasic cardiomyopathy 6 (2.6) 3 (2.6) 3 (2.6) 1.00
Other comorbidities* 38 (16.7) 26 (22.8) 12 (10.5) 0.01
Clinical presentation of Chagas disease
Indeterminate 195 (85.5) 90 (78.9) 105 (92.1) 0.02
Cardiac stage A 23 (10.1) 16 (14.0) 7 (6.1)
Cardiac stage B1 5 (2.2) 3 (2.6) 2 (1.8)
Cardiac stage B2 0 (0.0) 0 (0.0) 0 (0.0)
Cardiac stage C 5 (2.2) 5 (4.4) 0 (0.0)
CD specific ECG abnormalities 34 (14.9) 25 (21.9) 9 (7.9) 0.003
Second or third-degree right bundle-branch block 14 (6.1) 11 (9.7) 3 (2.6) 0.03
Frequent atrial or ventricular premature beats 5 (2.2) 3 (2.6) 2 (1.8) 0.65
Primary ST-T wave abnormalities 13 (5.7) 11 (9.7) 2 (1.8) 0.01
Electrical inactive area 4 (1.8) 2 (1.8) 2 (1.8) 1.00
Second or three-degree left bundle-branch block 2 (0.9) 1 (0.9) 1 (0.9) 1.00
Atrial flutter 1 (0.4) 1 (0.9) 0 (0.0) 0.32
Atrial tachycardia 1 (0.4) 1 (0.9) 0 (0.0) 0.32
Echocardiogram abnormalities (n = 172) 56 (32.6) 40 (42.1) 16 (20.8) 0.003
Diastolic dysfunction 42 (24.4) 32 (33.7) 10 (13.0) 0.002
Segmental dysfunction 19 (11.1) 14 (14.8) 5 (6.5) 0.09
Global systolic dysfunction 13 (7.6) 10 (10.5) 3 (3.9) 0.10
Serological cure 13 (5.7) 0 (0.0) 13 (11.4) <0.001

Other comorbidities included cancer, asthma, chronic obstructive pulmonary disease, hypothyroidism, depression, alcohol abuse, and co-infection (HIV, HTLV, and viral hepatitis).