Table 5.

Baseline characteristics of high risk patients compared with low risk patients.

Parameter		Dyspnoea <3 and PS <2 vs. dyspnoea >3 and PS >2			DLCO 〈50% vs. DLCO 〉 80%
		Low risk [Dyspnoea <3 and PS <2] (n-64)	High risk [Dyspnoea >3 and PS >2] (n = 28)	P	Low risk [DLCO > 80%] (n = 31)	High risk [DLCO <50%] (n = 33)	p
Gender	M:F	30:34	15:13	ns	19:12	18:15	ns
Age (years)	Mean (± 95%CI)	72.0 ± 2.08	73.8 ± 2.39	ns	72.4 ± 3.03	69.8 ± 2.77	ns
Performance status	0–1	61 (95.3)	4 (14.3)	0.00001	19 (53.3)	15 (45.5)	ns
	2–4	3 (4.7)	24 (85.7)		11 (36.7)	18 (54.5)
Dyspnoea score	0–2	64 (100)	0	n/a	17 (56.7)	12 (36.4)	ns
	3–5	0	28 (100)		13 (43.3)	21 (63.6)
Level of activity	Sedentary	33 (51.6)	26 (92.9)	0.0001	21 (70.0)	27 (81.8)	ns
	Active	31 (48.4)	2 (7.1)		9 (30.0)	6 (18.2)
Frailty	1–3	58 (92.1)	2 (7.1)	0.00001	22 (75.9)	14 (42.4)	0.01
	4–7	5 (7.9)	26 (92.9)		7 (24.1)	19 (57.8)
Smoking habit	Current smoker	7 (10.9)	7 (25)	ns	0 (0)	6 (18.2)	0.02
	Previous or never smoked	57 (89.1)	21 (75)		31 (100)	27 (81.8)
FEV1 (litres)	Mean (± 95%CI)	1.79 ± 0.19	1.78 ± 0.29	ns	2.0 ± 0.19	1. 4 ± 0.21	0.000014
DLCO (% predicted)	Mean (± 95%CI)	71.4 ± 5.74	62.95 ± 5.19	0.03	94.5 ± 13.82	42.1 ± 2.29	0.00001
Thoracoscore (%)	Mean (± 95%CI)	2.06 ± 0.54	4.76 ± 1.86	0.0003	2.1 ± 0.8	3.3 ± 2.1	Ns
6MWT (mts)	Mean (± 95%CI)	388.35 ± 29.19	139.61± 41.19	0.00001	376.5 ± 56.396	301 ± 44.695	0.023
Assessment to surgery days	Mean (± 95%CI)	35.3 ± 14.36	65.75 ± 51.85	0.03	39.75 ± 24.9	35.9 ± 14.6	Ns
Considered not fit for	Surgery	13 (20.3)	28 (100)	0.00001	11 (35.5)	26 (78.8)	0.0008
	Radiotherapy	5 (7.8)	10 (38.5)	0.001	3 (9.7)	11 (34.4)	0.03

Values are numbers (percentage) unless otherwise stated. P values were calculated using Fishers exact test for categorical data and t-test for independent continuous variables by excluding unknown data.

CI= confidence interval; IQR= interquartile range; ns= not significant, n/a = not applicable; 6MWT= six minute walk test.