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. 2021 Jan 29;6:18. doi: 10.1038/s41541-021-00281-z

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 7 — Mice (n = 5 per group) were injected intraperitoneally with 10 μg CFSE-labeled OMVs or saline and cellular exudate was harvested 6 h later by peritoneal lavage. a The percentage of DCs harboring OMVs and expressing b CD40, c CD80, d CD86, e MCH class I, and f MHC class II was assessed by flow cytometry. The levels of cytokines g IL-12p70, h IL-18, and i) IL-6 present in lavage fluid were measured by multiplex assay. *p < 0.05, **p < 0.01, ***p < 0.001 compared to saline by Student’s t test. Results are representative of two independent experiments.