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. 2021 Jan 29;12:687. doi: 10.1038/s41467-021-20907-z

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — The number of DMRs are shown in promoters (a), enhancers (b), transcribed regions (c), repressed regions (heterochromatin) (d), repetitive regions (e), non-repetitive regions (f), inside PMDs (g), and outside PMDs (h). The solid blue dots represent the means of normalized numbers of DMRs in IPNs of each histologic stage with a 95% confidence interval as error bars. The differences among all stages were assessed using the Kruskal-Wallis H test. Source data is provided as a source data file.