Fig. 3. Phylogenetic relationship and expression profiles of CYP71D gene family in Danshen genome.

a Phylogenetic analysis of Danshen CYP71D subfamily. Maximum likelihood method was used to construct the phylogenetic tree with 1000 replicate bootstrap support. The tree was rooted with the three CYP76 family members from Danshen previously shown to act in tanshinone biosynthesis. b Gene expression heatmap for the Danshen CYP71D subfamily members, as well as three CYP76 family members known to act in tanshinone biosynthesis, displaying relative expression level in root, stem, leaf, calyx, and petal of flowering plants. Source data underlying Fig. 3b are provided as a Source Data file.