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. 2021 Jan 29;11:2627. doi: 10.1038/s41598-020-80947-1

Table 2.

Mental and physical wellbeing according to Short-Form 12-item (SF-12) questionnaire in middle-aged adults receiving placebo or synbiotic for 30 days.

Placebo Synbiotic
Baseline Day 30 Baseline Day 30
Mental Component Score (MCS) 45 ± 10.8 46.8 ± 11.3 50 ± 7.2 48.4 ± 5.8
Physical Component Score (PCS) 51.5 ± 7.9 50.6 ± 6.1 52.9 ± 5 54.1 ± 4.2
Physical function 87.5 ± 23.5 89.3 ± 18.9 94.2 ± 15 94.2 ± 11
Role physical 85.7 ± 18.9 84.8 ± 18.5 92.3 ± 10.9 95.2 ± 9.6
Bodily pain 78.6 ± 23.7 83.9 ± 23.2 90.4 ± 12.7 94.2 ± 11
General health 65.4 ± 10.6 62.9 ± 15.2 66.9 ± 13.6 68.1 ± 15.8
Vitality 33.9 ± 21 28.6 ± 25.7 46.2 ± 13.9 38.5 ± 21.9
Social function 89.3 ± 16.2 83.9 ± 23.2 90.4 ± 12.7 90.4 ± 12.7
Role emotional 75.9 ± 19.3 84.8 ± 18.5 92.3 ± 10.9 90.4 ± 11.6
Mental health 66.1 ± 23.2 66.1 ± 23.2 74 ± 15.7 73.1 ± 13.4

Values are means ± SD (placebo: n = 14, synbiotic: n = 13). Matched-pairs Wilcoxon signed-rank tests were performed to compare changes from baseline (within-group variations; p > 0.05). Between-groups variations were analyzed by Mann–Whitney U-tests (p > 0.05).