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A. Venn-diagram indicating the number of down-regulated (green) and up-regulated (red) miRNAs after treatment of Calu-3 cells with R8-PNA-a101 and R8-PNA-a145, as indicated (FC > 3). In black are the total numbers of dysregulated miRNAs. Only 6 miRNAs (<1.29%) were dysregulated in Calu-3 cells treated with both the two anti-miRNAs PNAs.
