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. 2021 Jan 27;7(1):e06013. doi: 10.1016/j.heliyon.2021.e06013

Figure 6.

Figure 6

Comparison of WT and Mutated Structures for NF2: WT: Gold; Mutant 1: Red Glu463Lys). This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. This mutation does not change in any noticeable way, either the overall or the local structure in the neighborhood of the mutations as both the overall and local structure of the WT and mutated proteins overlap almost perfectly.